Public and Private Information Sharing under "New Normal" of COVID-19: Understanding the Roles of Habit and Outcome Expectation.

Information sharing is critical in risk communication and management during the COVID-19 epidemic, and information sharing has been a part of individual prevention and particular lifestyles under the "New Normal" of COVID-19. Thus, the purpose of this study was to explore influencing factors and mechanisms in public and private information sharing intention among people under the regular risk situation. This study investigated an information sharing mechanism based on a cross-sectional design. We collected 780 valid responses through a sample database of an online questionnaire platform and utilized partial least squares structural equation modeling (PLS-SEM) to further analyze the data. To explore the difference caused by news frames, we divided respondents into two groups according to the news frame (action frame vs. reassurance frame) and proceeded with the multi-group analysis. The results showed that four types of outcome expectations (information seeking, emotion regulation, altruism and public engagement) and habit had impacts on public and private information sharing intention. Two paths influencing information sharing proposed in this study were supported. The results showed that outcome expectations were positively related to habit, which implies that the cognitive mechanism was positively relevant to the formation of habit. The results proved that habit played a mediating role between outcome expectations and information sharing. This research found that emotion regulation and public engagement outcome expectations only affected two types of information sharing intention mediated by habit. Regarding the role of the news frame, this study found no significant difference between the group exposed to action-framed news and the group exposed to reassurance-framed news. By exploring influencing factors and the mechanism of information sharing under the "New Normal", these findings contribute to understanding of information sharing and have implications on risk management. The proposed mechanism classifying public and private information sharing complements risk information flowing by considering online risk incubation.

Pandemic Uncertainty and Socially Responsible Investments.

This paper examines the effects of pandemic uncertainty on socially responsible investments. We use the overall corporate sustainability performance index in the Global-100 Most Sustainable Corporations in the World dataset to measure socially responsible investments. The global pandemic uncertainty is also measured by the World Pandemic Uncertainty Index. We focus on the panel dataset from 2012 to 2020, and the results show that the World Pandemic Uncertainty Index is positively related to socially responsible investments. The main findings remain significant when we utilize various panel estimation techniques.

Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways.

Chronic obstructive pulmonary disease (COPD) is a chronic, progressive lung disease with few successful treatments, and is strongly associated with cigarette smoking (CS). Since the novel coronavirus has spread worldwide seriously, there is growing concern that patients who have chronic respiratory conditions like COPD can easily be infected and are more prone to having severe illness and even mortality because of lung dysfunction. Loquat leaves have long been used as an important material for both pharmaceutical and functional applications in the treatment of lung disease in Asia, especially in China and Japan. Total flavonoids (TF), the main active components derived from loquat leaves, showed remarkable anti-inflammatory and antioxidant activities. However, their protective activity against CS-induced COPD airway inflammation and oxidative stress and its underlying mechanism still remain not well-understood. The present study uses a CS-induced mouse model to estimate the morphological changes in lung tissue. The results demonstrated that TF suppressed the histological changes in the lungs of CS-challenged mice, as evidenced by reduced generation of pro-inflammatory cytokines including interleukin 6 (IL-6), IL-1ß, tumor necrosis factor α (TNF-α), nitric oxide (NO), and inducible nitric oxide synthase (iNOS) and diminished the protein expression of transient receptor potential vanilloid 1 (TRPV1). Moreover, TF also inhibited phosphorylation of IKK, IκB and NFκB and increased p-Akt. Interestingly, TF could inhibit CS-induced oxidative stress in the lungs of COPD mice. TF treatment significantly inhibited the level of malondialdehyde (MDA) and increased the activity of superoxide dismutase (SOD). In addition, TF markedly downregulated TRPV1 and cytochrome P450 2E1 (CYP2E1) and upregulated the expression of SOD-2, while the p-JNK level was observed to be inhibited in COPD mice. Taken together, our findings showed that the protective effect and putative mechanism of the action of TF resulted in the inhibition of inflammation and oxidative stress through the regulation of TRPV1 and the related signal pathway in lung tissues. It suggested that TF derived from loquat leaves could be considered to be an alternative or a new functional material and used for the treatment of CS-induced COPD.